Unable to load the application manifest file from the installation directory. File: %1 Cause: Either the file has been deleted ...

Lync Server 2010

Unable to load the application manifest file from the installation directory.

File: %1
Cause: Either the file has been deleted or the RTCSRV service account does not have the appropriate permissions to read from the file.
Resolution:
Verify that the file exists.  If it does not, reinstall Lync Server.  If it does exist, verify that the RTCSRV service account has permissions to read the file.  If the RTCSRV service account has read permissions on the file, then it is corrupted and you should reinstall Lync Server.

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