The Intersite Messaging service using the SMTP transport has received a delivery status report from the SMTP service for ...

The Intersite Messaging service using the SMTP transport has received a delivery status report from the SMTP service for a message it submitted that indicated delivery failure. 
 
Delivery status text:
%2 %3 
 
This may be a permanent or a transient condition. Active Directory Domain Services will try this operation again later when it sends another replication message according to the schedule of the intersite connection. 
 
User Action 
-If the SMTP service has given up too quickly, adjust the SMTP retry parameters using the SMTP service manager. 
 
-If the destination domain controller is unknown or not directly connected to the local domain controller, it may be necessary to configure  SMTP to use a gateway to route the mail to the target system. You can do this using the SMTP service manager. 
 
-If the DNS address for the destination domain controller cannot be resolved, or if network connectivity cannot be established, consult your network administrator. 
 
-If the mail message is too large, either increase the message size limit of the SMTP service or disable limit checking. 
 
Additional Data 
Error value:
%1 %4