Enables loading managed PDB files on this computer (the target computer) when the PDB file cannot be found on the Visual ...

Enables loading managed PDB files on this computer (the target computer) when the PDB 
                file cannot be found on the Visual Studio computer. When enabled, the debugger will search
                in the path where the PDB was originally built and also next to where the dll/exe is 
                currently located. This option may have a performance impact on remote debugging since now
                any queries for the PDB will go over the network, but it is minimal in typical cases.